Protein Details: Aquaglyceroporin

Protein ID

ICDB_Pro_1252

Protein Name

Aquaglyceroporin

Gene Name

AQP; PF3D7_1132800

Organism

Plasmodium falciparum (isolate 3D7)

Length

258 amino acids

AlphaFoldDB

AF-Q8II36-F1-model_v4.pdb

Function

Mediates water and glycerol transport across the cell membrane. Permeable to sugar alcohols of up to five carbons and urea. Permeable to ammonia; methylamine and formamide.

Sequence

MHMLFYKSYVREFIGEFLGTFVLMFLGEGATANFHTTGLSGDWYKLCLGWGLAVFFGILVSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQFYDKVICPLVDLANNEKDGVDL

PDB Structures

3C02

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1074/jbc.m110683200; 10.1038/nature01097; 10.1111/j.1365-2958.2006.05325.x; 10.1038/nsmb.1431

RefSeq

XP_001348009.1